HISTORY OF SANTEN
1890
Heburin-gan and the founding of SantenFounder Kenkichi Taguchi opens Taguchi Santendo in Kitahama, Osaka. Santen's main product at the time of establishment was a cold medication called Heburin-gan.

1899
The first eye drops of the Company Daigaku Eye Drops launchedIt's said that many physicians who came to Japan from abroad during the Meiji Period from the end of the 19th century to the beginning of the 20th century were astonished at the prevalence of eye disorders among the people of the country. This observation was indicative of the large demand for ophthalmics at the time. To respond to this potential market, Santen launched the Daigaku Eye Drops brand. The ambitious ad campaign for this new product featured the catchphrase "A great eye drop for a rapidly modernizing society" along with the image of a distinguished college professor sporting a full beard and glasses. This trademarked image soon became extremely popular nationwide.

1925
Operations incorporated as Santendo Co., Ltd. Chuko Mita is appointed first presidentTo develop its business, Santendo Co., Ltd. is established with Chuko Mita as its first president. Major products at that time include Heburin-gan, Daigaku Eye Drops, Santen Cough Medicine, and constipation treatment Kentsu-gan.

1935
Opening of the Yodogwa PlantYodogawa Plant established in Higashi Yodogawa-ku, Osaka (where the Head Office is subsequently established). When it first commenced operations, the plant mainly produced eye drops, menthol creams, antacids, gastrointestinal medication, antipyretics, antihelminthics, antidiarrheals, analgesics, antitussives and minor wound medication, among other types of drugs.

1952
Daigaku Penicillin Eye Drops, Daigaku Mycillin Eye Drops, and Daigaku Super Eye Drops launched in 1952, 1953, and 1954, respectivelyLaunch of a business strategy focusing on eye drops for corporate reconstruction.

1958
Expansion into the prescription drug marketCompany renamed as Santen Pharmaceutical Co., Ltd. (current name). Now accounting for more than 90% of all corporate sales, the prescription drug business (in other words, the manufacturing and marketing of drugs prescribed by health care establishment) has grown to become Santen's core enterprise. In 1962, Santen acquired the domestic marketing rights for the mydriatic Midorin-P (generic name: tropicamide) from the Swiss pharmaceutical company Roche and began sales of this treatment in Japan. A groundbreaking drug that promotes mydriasis, or dilation of the pupil, Midorin-P contributed to the advancement of ophthalmic surgery and diagnosis and helped Santen enhance its stature in the field of prescription ophthalmics.

1962
The launch of Super Sante the introduction of Japan's first plastic eye drop containerEye drops used to be packaged in glass containers, which had its drawbacks. These containers were difficult and expensive to produce in large volumes because they were hand-made and also had a tendency to break at times. The new Super Sante featured Japan's first plastic eye drop container that was easy to carry and use. The product along with its unique container became widely popular among consumers and triggered a rapid expansion of eye drop sales in Japan.

1977
Listed on the first section of the Tokyo Stock Exchange and the Osaka Securities ExchangeIn this year, Santen increased its capitalization to 1,102 million yen and achieved a sales record of 9,000 million yen.
1985
Noto Plant established
The Noto Plant was Santen's first production base equipped with a factory automation system, and evolved to become one of the world's largest eye drop manufacturing operations. The plant is currently Santen's flagship factory and produces top-selling ophthalmics such as Cravit and Hyalein.

1990
Long-term vision drawn up for Santen's 100th anniversaryOn the centennial of Santen's founding, the Company announces its long-term vision: "To contribute to society with the best products and services focusing on the eye and health"; and devises management objectives focusing on becoming " a world-class company" and a "leader in all areas of ophthalmic treatments".
1992
TAHMIN SANTEN CO., LTD. established in Taiwan1993
Subsidiary Santen Inc. established in the U.S.U.S. subsidiary Santen Inc. established. Santen Inc. conducts R&D, business development and strategic marketing activities in the U.S.

1996
Nara Research and Development Center and Shiga Plant opened

2000
Santen Pharmaceutical Korea, Co., Ltd. established2007
Suzhou Plant established in China
2010
Santen Pharmaceutical Korea Co., Ltd. commenced marketing2011
Santen India Private Limited established2012
Santen Holdings EU B.V. established as a holding company
2013
Santen Pharmaceutical Asia Pte.Ltd. established in Singapore
Ho Chi Minh Representative Office established
2014
Established subsidiaries in Switzerland, Italy, the U.K., Spain, Thailand, Malaysia and the Philippines
2016
Established SANTEN PHARMACEUTICAL (HONG KONG) LIMITED
2018
Established INDONESIA REPRESENTATIVE OFFICE
TODAY
Santen has grown into a leading ophthalmic pharmaceutical company in the world and the top manufacturer of prescription ophthalmic pharmaceuticals in Japan. Sales of prescription ophthalmic pharmaceuticals account for over 80% of Santen's total net sales.